منابع مشابه
Bridging structural biology and genomics: assessing protein– protein interaction datasets
Currently, there is a major effort to map protein–protein interactions on a genome-wide scale. The utility of the resulting interaction networks will depend on the reliability of the experimental methods and the coverage of the approaches. Known macromolecular complexes provide a defined and objective set of protein interactions with which to compare biochemical and genetic data for validation....
متن کاملStructural genomics
theory, based on the shape and location of coral formations, on coral’s inability to grow at depths greater than 30 fathoms, and most of all on a scenario for which he had no evidence: that each reef or atoll represents the outer limit of an island that has slowly subsided into the ocean. Read this chapter, if only to be struck by its masterly fusion of acute observation and trenchant imaginati...
متن کاملNMR and structural genomics.
The role of NMR in structural genomics is outlined, with particular emphasis on using protein domains as targets. Strategies for domain expression, characterization, and labeling are presented.
متن کاملFocusing in on structural genomics: the University of Queensland structural biology pipeline.
The flood of new genomic sequence information together with technological innovations in protein structure determination have led to worldwide structural genomics (SG) initiatives. The goals of SG initiatives are to accelerate the process of protein structure determination, to fill in protein fold space and to provide information about the function of uncharacterized proteins. In the long-term,...
متن کاملStructural biology
doesn't know which Academy member is handling the paper unless it is accepted. To make room for the extra papers to be submitted via track II, PNAS has reduced the number of papers a member is allowed to communicate to the journal annually from six to four. Does the new system work? Those who have tried it say that there are many frustrating teething problems. Apparently one problem is that the...
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ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 2000
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.40.304